RALI Maine is an alliance of local, state and national organizations elevating solutions to the opioid epidemic in the state.

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The Rx Abuse Leadership Initiative (RALI) of Maine is an alliance of organizations elevating programs that have a real impact on our state’s opioid crisis.

Addressing Maine’s
opioid epidemic together.

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About Us

According to the Centers for Disease Control and Prevention (CDC), Maine is among the top ten states with the highest rates of opioid-related overdose deaths. In 2017, 360 Mainers died of an opioid-related overdose.

We must come together to help individuals and families who are struggling with addiction and provide communities with resources to prevent substance misuse.

RALI Maine and its partners support a broad range of programs, including prevention, treatment and recovery services. Initially, we are focused on facilitating the safe disposal of unused prescription medicines and raising awareness of the warning signs of opioid misuse.



Making a


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If you know of organizations, events or individuals making a difference in your
community, we want to hear about them. Fill out this short form.


Safe Use &


Everyone can help prevent prescription drug misuse by safely using, storing and disposing of medications.   

  • Always talk to your doctor about how to use a prescription medication before taking it.

  • Be sure to follow dosing recommendations closely.

  • Don't mix medications without first checking with your doctor.

  • Never mix prescription opioids with alcohol.

  • Don't take someone

       else's medication



  • Always keep prescription medications in a locked or secure place – and out of the reach of children.

  • Have a family conversation about the dangers of misusing prescription medication.

  • Never share medications with family members.


  • When finished using a
    prescription medication as
    directed by a medical
    professional, safely dispose of it rather than keep it in your medicine cabinet for future use.


  • Below are several ways to easily and safely dispose of unused medications. Visit the FDA website or talk to your doctor about the disposal method best suited for your medication.

One of the best things we can all do to help address the opioid crisis in our state is to safely dispose of unused prescription medications.


You can use household
materials to dispose of your unused medications. All you have to do is mix your
medicines with kitty litter or old coffee grounds in an
airtight container and
dispose of it in your trash can.

There are several options:


You can visit a drug takeback center in
your community.

Click HERE to find locations in Maine.


You can use a home
disposal kit – just put unused medications
in the included pouch, add water, seal and
dispose of it in the




If someone you know has started misusing opioids, early intervention is important. Learning the warning signs of opioid addiction can help protect your family,

friends and communities.


Physical and behavioral changes could indicate someone is misusing prescription opioids or illegal drugs, like heroin or fentanyl.

Common signs of opioid misuse:






Increase in fatigue or drowsiness

Rapid weight loss

Frequent constipation or nausea

Decline in personal hygiene

Wearing long sleeves regardless of the season

Unexplained absences from school or work

Drop in grades or performance at work

Loss of interest in hobbies

Spending less time with friends or family

Hanging out with a new friend group

Missing prescription medications

Empty pill bottles

Paraphernalia, such as syringes, shoe laces or rubber hose, kitchen spoons, aluminum foil, straws, lighters

Spotting warning signs in teenagers can be particularly hard because young people go through many emotional and physical changes.


If you suspect a loved one is misusing opioids, there are resources that can help you prepare for a conversation with them.  It’s also important to talk to your family doctor about prevention and treatment options.


News & Updates

December 17, 2019

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